Methodology & Workflow

Based on clinical data, and on the available literature we aim to quantify personalized dosimetry on the most critical organs in children (2-15 years old), and create a universal tool for the total calculation of the absorbed dose per organ, according to the:

  • Specified radiopharmaceutical biodistributions
  • Injected activity
  • X-ray model irradiation
  • Brachytherapy source model and irradiation type
  • Anatomical characteristics (age, weight, height, gender)

The creation of the dosimetric software will be based on:

  • Accurate physical processes modeling
  • Realistic MC simulations incorporating biokinetics
  • High resolution anthropomorphic computational models
  • Powerful computational resources (grids, GPU, HPC)

7 Working Packages are connected towards this effort.